自愈水凝胶
多糖
聚合物
壳聚糖
共价键
透明质酸
化学工程
高分子化学
高分子科学
化学改性
化学
天然聚合物
材料科学
有机化学
工程类
生物
遗传学
作者
Daniela Pasqui,Milena De Cagna,Rolando Barbucci
出处
期刊:Polymers
[MDPI AG]
日期:2012-08-21
卷期号:4 (3): 1517-1534
被引量:143
摘要
Different hydrogels were prepared starting from natural or semi-synthetic polysaccharides (carboxymethylcellulose, hyaluronic acid and chitosan) which were cross-linked by the addition of a cross-linking agent chosen according to the chemical groups present along the polymer chains. The cross-linking reaction allows for the formation of a three-dimensional network made of covalent bonds between the polymer chains, which is stable under physiological conditions. The presence of a substantial amount of water within the polysaccharide matrices makes such systems unique among hydrophilic gels. Water itself is responsible for some of their peculiar characteristics, one of which is their injectability which makes these hydrogels suitable for using as matrices for mini-invasive surgery and localized therapy.
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