The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2026

This is an update on the European Federation of Societies in Ultrasound, Medicine and Biology (EFSUMB) contrast enhanced ultrasound (CEUS) non-hepatic applications guidelines which were last updated in 2017. There has been consolidation of some of the previous applications, particularly, renal and urology, which are now part of routine clinical practice. The most number of publications and areas of research interest have been in the use of CEUS in bowel, endoscopic ultrasound and in neurosonology. A few novel applications have also been tried and show promise, such as in the parathyroids and salivary glands whilst there are a few areas which have previously been researched relatively extensively but have yet to find their clinical utility. Nonetheless, the use of CEUS and its applications have been steadily growing and it is timely that there has been another update on these guidelines which come, as usual, with recommendations on its use from an expert panel.