Research progress of regulatory T cells in female reproductive process

Regulatory T cells (Tregs) are a subtype of lymphocytes with immune suppressive function, and are abundantly expressed on ovarian and endometrium. They have the functions of regulating follicular development, suppressing immune response, promoting maternal-fetal immune tolerance and maintaining early pregnancy during reproduction. The abnormal expressing of Tregs is closely related to the occurrence and development of female reproductive diseases, and it is expected to become a new diagnostic marker and therapeutic target in reproductive medicine. Key words: Regulatory T cell; Infertility; Follicular development; Immunological tolerance