Global disparities in faecal microbiota transplantation research

Faecal microbiota transplantation (FMT) is recommended therapy for recurrent Clostridioides difficile infection in adult and paediatric patients 1 McDonald LC Gerding DN Johnson S et al. Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Clin Infect Dis. 2018; 66: e1-48 Crossref PubMed Scopus (806) Google Scholar and is being explored as treatment for a growing range of microbiome-mediated diseases. 2 Allegretti JR Mullish BH Kelly C Fischer M The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications. Lancet. 2019; 394: 420-431 Summary Full Text Full Text PDF PubMed Scopus (95) Google Scholar Although microbiome-based therapies could play a key role in global health, 3 Porras AM Brito IL The internationalization of human microbiome research. Curr Opin Microbiol. 2019; 50: 50-55 Crossref PubMed Scopus (10) Google Scholar , 4 Rogers GB Ward J Brown A Wesselingh SL Inclusivity and equity in human microbiome research. Lancet. 2019; 393: 728-729 Summary Full Text Full Text PDF PubMed Scopus (7) Google Scholar global FMT research remains inequitably distributed.