随机对照试验
梅德林
系统回顾
医学
双相情感障碍
循证医学
心理学
精神科
替代医学
内科学
心情
病理
生物
生物化学
作者
Vincent Hede,Sophie Favre,Jean-Michel Aubry,Hélène Richard-Lepouriel
标识
DOI:10.1016/j.psychres.2019.112627
摘要
Bipolar spectrum disorder (BSD) is an extended concept of bipolar disorder (BD) that includes conditions that do not fulfill the criteria. There is no recommendation today about its treatment. We reviewed relevant literature focusing on pharmacological treatments, looking for high-strength evidence leading to guidelines.A literature search was conducted using MedLine / PubMed database and Google Scholar up to September 2018. Search words were related to BSD and pharmacological treatment.The literature search yielded 621 articles. Out of these, 35 articles met our selection criteria. There was limited high quality data. Only one randomized control trial (RCT) and one randomized open label trial were found. Most studies used different definition of BSD.There is a considerable lack of data and no evidence supporting efficacy of pharmacological treatment for BSD. There is a need for a consensus on the definition of BSD and more evidence studies to evaluate drug's effectiveness in this condition.
科研通智能强力驱动
Strongly Powered by AbleSci AI