Effect of CRH on phagocytosis of rat enterocoelia macrophage

Objective To explore the effect of corticotropin-releasing hormone(CRH) on phagocytosis of rat enterocoelia macrophage.Methods The chicken-red cells were added in the media of rat enterocoelia macrophage cultivated by CRH after 1、2、4、8、16 hours.Then the effect of CRH on phagocytosis of rat enterocoelia macrophage was evaluated by the chicken-red cells phagocytosis index and phagocytosis rate.Results Comparing with the control groups,the phagocytosis index and phagocytosis rate of experimental groups both improved significantly in each time point(P0.05).Among the experimental groups,the phagocytosis index and phagocytosis rate were the highest and the phagocytosis was at the top in the 2 hours group.Conclusion CRH could markedly improve the phagocytosis of rat enterocoelia macrophage.