Analysis on the Role of Cryoprecipitate in Improvement of Coagulation Abnormalities in Patients with Tumors

Objective To explore the correction effect of cryoprecipitate on coagulation abnormalities in patients with tumors. Methods Fifteen patients with tumors were treated with cryoprecipitate when they showed coagulation abnormalities for the first time.The treatment last for 1～5 days,and the blood platelet and blood coagulation function were monitored each day of the treatment. Results There were statistically significant differences in the coagulation indexes except PLT among 15 tumors patients during the period of treatment with different frequencies and different doses of cryoprecipitate. Conclusions Rational use of cryoprecipitate can improve hemoglutination function barrier and reduce the infusion of blood plasma when tumor patients present obvious coagulation abnormalities.But the frequency and the dose of cryoprecipitate supplement should decide in accordance with the monitoring result of conventional blood coagulation combined with the patient's actual condition.