In this article,we apply autoclave leaching process of treatment for tellurium in complicated materials,and make some studies on the influences which concentration of NaoH,the ratio of solid to liquid,leaching time,leaching pressure and leaching temperature to the effect of leaching.The result shows that the leaching effect is the best with the conditions of Tellurium NaoH concentration of 40g·L-1,the solid to liquid rate of 1:7,leaching time of 6h,leaching pressure of 0.9MPa,leaching temperature of 120℃.If tellurium of precious metals is reclaimed in the shape of TeO2,the recovery rate will be over 95%.