Content change of triptolide in Tripterygium wilfordii compatible with four Chinese crude drugs

OBJECTIVE To determine the content variation of triptolide when Tripterygium wilfordii respective compatible with Red Peony Root,Radish Seed,Finger Citron and Bamboo Shavings,and to study the rationality of the traditional Chinese drug compatibility.METHODS Decocted respectively the Tripterygium wilfordii and the four Chinese crude drugs with water,and evaluated the triptolide by HPLC.RESULTS The content of triptolide in the decoction of Tripterygium wilfordii compatible with Finger Citron was higher than Tripterygium wilfordii by 25% with statistical treatment,while the content in others had no significant change.CONCLUSION Finger Citron may obviously increase the content of triptolide.Red Peony Root,Radish Seed and Bamboo Shavings had quiet influence on it.