Paclitaxel and docetaxel.

Objective To provide the basis for the clinical application of paclitaxel and docetaxel,compare their differences on pharmacological profiles and patterns of clinical activity. Methods The literature of taxanes was analyzed. Results The two taxanes differed in structures,pharmacokinetic charateristics,drug interactions,toxicity and administrations. Conclusion The rational use of the two taxanes should be based on their differences.