医学
慢性疼痛
围手术期
急性疼痛
金标准(测试)
临床试验
神经轴阻滞
麻醉
心胸外科
随机对照试验
疼痛管理
类阿片
重症监护医学
外科
物理疗法
内科学
受体
脊髓麻醉
作者
Cory Maxwell,Alina Nicoara
标识
DOI:10.1097/aco.0000000000000029
摘要
This review examines recent advances and findings in the field of pain management in patients undergoing thoracic surgery.Acute and chronic postoperative pain continues to remain a major problem and a primary concern for patients. Although thoracic epidural analgesia is still considered a 'gold standard', more evidence exists that paravertebral blockade has similar efficacy with a better side-effect and safety profile. The cornerstone of pain management remains a multimodal therapeutic strategy that provides both a central and a peripheral block by combining regional techniques with opioid and nonopioid analgesics.Pain after thoracic surgery has a profound impact on perioperative outcome. Beyond the immediate perioperative period, acute pain contributes to the development of the debilitating chronic pain syndrome. Going forward, both procedural and pharmacologic interventions for acute and chronic pain should be studied in definitive multicenter, well designed randomized clinical trials.
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