A New Monoterpene Rhamnoside from Cercis glabra Legumes

A new monoterpene rhamnoside, (+)-(R)-α-terpineol α-L-rhamnoside (1), along with ten known compounds (2-11) were obtained after purification of the ethanol extract of Cercis glabra legumes.Their structures were elucidated by spectroscopic evidence including NMR, optical rotatory dispersion (ORD), HR-ESI-MS and chemical hydrolysis.In the acetylcholinesterase inhibitory assay, compounds 3 and 8 showed high percentages of inhibition which were comparable to the activity of donepezil (a commercial drug, the positive control), and exhibited IC50 values of 0.488, 0.391 mg/mL.These bioactive components could be promising acetylcholinesterase inhibitors.