Prospective Validation of the First US FDA-Approved Computer-Aided Quality Assessment Tool for Colonoscopy: An Initial Clinical Experience

INTRODUCTION: We report a prospective pilot of GI Genius ColonPro 4.0 (Medtronic, Minneapolis, MN), the first US Food and Drug Administration-approved computer-aided quality (CAQ) platform for colonoscopy. METHODS: ColonPro measurements of withdrawal time, cecal intubation, and Boston Bowel Preparation Score (BBPS) were compared with independent video review in 110 outpatient colonoscopies. RESULTS: Agreement between the CAQ and physicians was poor for BBPS (intraclass correlation coefficient = 0.40, P < 0.001) but strong for withdrawal time (intraclass correlation coefficient = 0.89, P < 0.001) and cecal intubation (κ = 0.79, P < 0.001). DISCUSSION: CAQ reliably measures withdrawal time and cecal intubation, but artificial intelligence-based BBPS scoring requires further validation before integration into current paradigms of colonoscopy quality.