A novel and convenient method for the synthesis of 1,2,4‐oxadiazole‐5‐thiones

Abstract A novel and convenient method for the synthesis of 1,2,4‐oxadiazole‐5‐thiones with carbon disulfide as effective C=S source has been developed in a super basic condition. The presented method has a broad substrate scope, and various corresponding 1,2,4‐oxadiazole‐5‐thiones have been obtained in good to excellent yields. This method allows to the gram‐scale synthesis of products. Under similar conditions, synthesis of diazole thione benzothioamide derivative from p‐ cyanobenzamidoxime with CS 2 has been successfully achieved.