诺如病毒
杯状病毒科
爆发
流行病学
病菌
感染控制
病毒学
免疫学
疾病
医学
病毒
生物
重症监护医学
内科学
作者
Elizabeth Robilotti,Stan Deresinski,Benjamin A. Pinsky
摘要
Norovirus, an RNA virus of the family Caliciviridae, is a human enteric pathogen that causes substantial morbidity across both health care and community settings. Several factors enhance the transmissibility of norovirus, including the small inoculum required to produce infection (<100 viral particles), prolonged viral shedding, and its ability to survive in the environment. In this review, we describe the basic virology and immunology of noroviruses, the clinical disease resulting from infection and its diagnosis and management, as well as host and pathogen factors that complicate vaccine development. Additionally, we discuss overall epidemiology, infection control strategies, and global reporting efforts aimed at controlling this worldwide cause of acute gastroenteritis. Prompt implementation of infection control measures remains the mainstay of norovirus outbreak management.
科研通智能强力驱动
Strongly Powered by AbleSci AI