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Antimicrobial activity and isolation and identifition of the secondary metabolites from endophytic fungi DS58 of Decaisnea fargesii
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| 其它 | Six known compounds had been isolated from the Aspergillus.niger DS58 of Decaisneafargesii.Their structures were identified by physicochemical properties and spectra analysis.Six compounds were obtained and identified as 4-methoxy-6-(3-methyl-butyryl)-pran-2-one,campyrone A,3-hydroxy-3-(methoxycarbonyl)pentanedioic acid,4-acetamidobutanoic acid,malformin A1 and asperpyrones A.4-methoxy-6-(3-methyl-butyryl)-pran-2-one is a new one which was isolated from the natural.3-hydroxy-3-(methoxycarbonyl)pentanedioic acid was isolated from the culture of the fungi for the first time.Compounds′antibacterial activity and antioxidant activity test showed that the 2,5-dihydroxy benzeneacetic acid and its derivatives are widely bacteriostasis and good antioxidant activity,3-hydroxy-3-(methoxycarbonyl)pentanedioic acid has an effectively inhibit in plant pathogenic fungi.The MIC of Botrytis cinerea and Alternaria brassicae(Berk.)is 31.5μg/mL. |
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(2025-6-4)