A NaHCO3 Promoted Three‐component Cyclization: Easy Access to Benzodisulfide Heterocycles

Abstract A facile route for the synthesis of benzodisulfide heterocyclic compounds via a NaHCO 3 ‐promoted three‐component reaction between 2‐halophenylacetic acids, elemental sulfur (S 8 ) and amines under metal‐free conditions has been demonstrated. This transformation from available starting materials shows good functional group tolerance, and the target compounds can be derivatized for further application.