Retrospective analysis of increased levels of aspartate transaminase and alanine transaminase in hospitalized children

Drug-induced liver injury was most common in clinical therapy.The levels of alanine transaminase(ALT)and aspartate transaminase(AST)in 1242 in-patient children and 953 healthy chidren were analyzed in this paper.A significantly high levels of AST and ALT activity (more than 40IU/L)were observed in in-patient children,being 26.08% and 31.00% as com- pared to that of 3.99% and 3.16% in healthy children,respectively,showing significant difference.