INFLUENCE OF THERMAL-ELECTRICAL PARAMETER COMBINATIONS ON THERMAL LESIONS OF RADIOFREQUENCY TUMOR ABLATION

Several studies have been conducted on the applicability of hyperthermia radiofrequency in the treatment of liver tumors. Many theoretical studies have reported the relevance of various physical parameters in terms of their efficacy in combating tumors and have analyzed the impact of these physical parameters on the temperature profile in the diseased tissue. Parameters such as thermal and electrical conductivities have been investigated during simulations of thermal ablation. Such parameters play an important role in the process of heat transfer in tissues. The purpose of this study is to predict the lesion volume, considering the inclusion of temperature dependence of thermal-electrical properties. This paper introduces a three-dimensional computational model that includes different comparative combinations of tissue thermal-electrical parameters as a mapping of temperature (such as thermal and electrical conductivities and specific heat). The finite-element method is employed for simulating hepatic radiofrequency ablation through the numerical solutions of the bioheat, Laplace, and Navier–Stokes equations. The results suggest that different combinations of tissue temperature-dependent parameters can significantly affect the computed lesion volume and that the temperature dependence of electrical conductivity has a major impact on the computed lesion volume and temperature distribution.