NOUBA Project Novel Natural Molecules Inhibiting the Development of Marine Bacteria in Biofilms

Marine organisms represent a rather unexplored source of new activity and biological functions of molecules for biotechnologies. The research in\nchemical ecology of the marine environment leads to looking at metabolites of recognition or defence produced by these models. Marine bacteria\nbelonging to the Pseudoalteromonas genus of the Gammaproteobacteria class are often found in association with marine eukaryotes, and their\nability to produce a variety of biological activities attracted a particular attention. The marine Pseudoalteromonas sp. 3J6 and D41 were selected for\ntheir capacity to inhibit the biofilm formation of other bacteria. The study of antibiofilm metabolites synthesised by marine bacteria 3J6 and D41\nbiofilms can lead to the development of new anti-fouling compounds or applications in surface hygiene. The main originality of these compounds is to\nbe specifically antibiofilm, they have no activity against planctonic bacteria.