During the current times endurance to bear the symptoms of fever is less with a lowered pain threshold and the most of the individuals demand for instantaneous relief from pain and fever. Antipyretic and analgesic drugs that are being prescribed in modern medicine give instantaneous relief but public with some amount of awareness about the side effects wish to opt for safe and effective herbal remedies. This attitude necessitates the research for the evaluation of fast acting analgesics and antipyretics. Keeping this in view, a study has been planned to evaluate the antipyretic and analgesic properties of Amalakyadigana (total Gana - Amalaki, Haritaki, Pippali, Chitraka) in experimental animals.