抗性(生态学)
新陈代谢
化疗
癌症研究
生物
医学
遗传学
内科学
生态学
作者
Fahimeh Ghasemi,Tahereh Farkhondeh,Saeed Samarghandian,Alireza Ghasempour,Mehdi Shakibaie
出处
期刊:Current Molecular Medicine
[Bentham Science]
日期:2023-06-22
卷期号:23
标识
DOI:10.2174/1566524023666230622104625
摘要
Metabolic reprogramming in cancer cells is a strategy to meet high proliferation rates, invasion, and metastasis. Also, several researchers indicated that the cellular metabolism changed during the resistance to chemotherapy. Since glycolytic enzymes play a prominent role in these alterations, the ability to reduce resistance to chemotherapy drugs is promising for cancer patients. Oscillating gene expression of these enzymes was involved in the proliferation, invasion, and metastasis of cancer cells. This review discussed the roles of some glycolytic enzymes associated with cancer progression and resistance to chemotherapy in the various cancer types.
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