Synergy of secoisolariciresinol diglucoside and fructooligosaccharide in enhancement of the intestinal mucus barrier by relieving ER stress and regulating the gut microbiome

We found that the intervention of SDG and FOS exhibited a synergistic effect in enhancing the intestinal mucous barrier. SDG might be superior in relieving ER stress, while FOS primarily regulates the gut microbiota.