Smart Organic–Inorganic Polyoxomolybdates in Forward Osmosis for Antiviral-Drug Wastewater Treatment and Drug Reclamation

The demand to effectively treat medical wastewater has escalated with the much greater use of antiviral drugs since the COVID-19 pandemic. Forward osmosis (FO) has great potential in wastewater treatment only when appropriate draw solutes are available. Here, we synthesize a series of smart organic-inorganic polyoxomolybdates (POMs), namely, (NH₄)₆[Mo₇O₂₄], (PrNH₃)₆[Mo₇O₂₄], (ⁱPrNH₃)₆[Mo₇O₂₄], and (BuNH₃)₆[Mo₇O₂₄], for FO to treat antiviral-drug wastewater. Influential factors of separation performance have been systematically studied by tailoring the structure, organic characteristics, and cation chain length of POMs. POMs at 0.4 M produce water fluxes ranging from 14.0 to 16.4 LMH with negligible solute losses, at least 116% higher than those of NaCl, NH₄HCO₃, and other draw solutes. (NH₄)₆[Mo₇O₂₄] creates a water flux of 11.2 LMH, increased by more than 200% compared to that of NaCl and NH₄HCO₃ in long-term antiviral-drug wastewater reclamation. Remarkably, the drugs treated with NH₄HCO₃ and NaCl are either contaminated or denatured, while those with (NH₄)₆[Mo₇O₂₄] remain intact. Moreover, these POMs are recovered by sunlight-assisted acidification owing to their light and pH dual sensitivity and reusability for FO. POMs prove their suitability as draw solutes and demonstrate their superiority over the commonly studied draw solutes in wastewater treatment.