A logistic regression analysis of related factors for red blood cell transfusion

Objective To evaluate the clinical factors associated with red blood cell transfusion effectiveness.Methods446 patients(566 transfusions) received red blood cell transfusion from Jan 2008 to Jun 2010 were analyzed retrospectively.807 and 85 patients were in the effective transfusion and ineffective transfusion group respectively.The potential factors associated with red blood cell transfusion effectiveness were evaluated by the method of Logistic regression.Results The single factor analysis showed that blood transfusion history(χ2= 81.49,P = 0.00),the infection(χ2= 33.32,P =0.00),the splenohepatomegalia(χ2= 4.81,P = 0.03),and the malignant disease(χ2= 105.7,P = 0.00) were associated with the effectiveness of red blood cell transfusion.Binary conditional logistic regression analysis showed that the blood transfusion history(OR = 2.41,P = 0.001) and the malignant disease(OR = 2.86,P = 0.00) were independent factors for effectiveness of red blood cell transfusion.Conclusion The patients with blood transfusion history and malignant disease were at the high risk for ineffectiveness of red cell blood transfusion.