A new refrigerant mixture HFC152a/HFC125 (mass: 85/15) was proposed to replace the refrigerant CFC12. On basis of the software REFPROP 7.0, a computer program calculating thermodynamic properties of refrigerants was developed and the thermodynamic properties of the new refrigerant mixture were calculated. The pressure-enthalpy diagram and the saturated properties of this new refrigerant mixture were presented.