Calcium Hydroxide Is an Efficient Catalyst for Synthesis of Polyhydroxy Chalcones

Abstract Calcium hydroxide was found to be an efficient catalyst for synthesis of polyhydroxy chalcones. This method has been employed to synthesize various 2′,4′-dihydroxychalcones having various substituents on the B ring. The merits of this method include shorter reaction time, inexpensive and easily available catalyst, high yield, and easy workup compared to other reported methods. Keywords: aldehydecalcium hydroxidecondensationpolyhydroxy chalcone2,4-dihydroxyacetophenone