A single number for advocacy and communication—worldwide more than 850 million individuals have kidney diseases

On a world scale the total number of individuals with chronic kidney disease (CKD), acute kidney injury (AKI), and those on renal replacement therapy (RRT) exceeds 850 million, a truly concerning figure that is twice the estimated number of people with diabetes worldwide and >20 times higher than the number of individuals affected by AIDS/HIV worldwide. Thus kidney diseases are one of the most common diseases worldwide. Urinary Dickkopf-3 and kidney injury in patients with chronic pulmonary diseaseKidney InternationalVol. 100Issue 5PreviewDickkopf-related protein 3 is a stress-induced, epithelial cell–derived glycoprotein that is promoted as a prognostic as well as a predictive urinary biomarker in acute and chronic kidney disease. Schunk et al. provided evidence that Dickkopf-related protein 3 identifies patients with chronic obstructive pulmonary disease and preserved kidney function at increased risk for a loss of estimated glomerular filtration rate and deterioration of pulmonary function. Experimental data highlighted Dickkopf-related protein 3–related pathophysiological similarities and interactions between chronic kidney disease and chronic obstructive pulmonary disease. Full-Text PDF