双生的
化学
部分
环丙烷
烷基
电泳剂
重排
药物化学
有机化学
立体化学
催化作用
戒指(化学)
作者
Qiang Wang,Maria Biosca,Fahmi Himo,Kálmán J. Szabó
标识
DOI:10.1002/anie.202109461
摘要
The electrophilic fluorination of geminal alkyl substituted vinyl-Bmida derivatives proceeds via bora-Wagner-Meerwein rearrangement. According to DFT modelling studies this rearrangement occurs with a low activation barrier via a bora-cyclopropane shaped TS. The Bmida group has a larger migration aptitude than the alkyl moiety in the Wagner-Meerwein rearrangement of the presented electrophilic fluorination reactions.
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