Asymmetric hydrogenation of 1,4-diketones: facile synthesis of enantiopure 1,4-diarylbutane-1,4-diols

Presented herein is anIr/ f -amphox-catalyzed asymmetric hydrogenation for accessing enantiopure 1,4-diarylbutane-1,4-diolsin superb yields with exceptional stereoselectivities.