医学
重症监护医学
药品
药物开发
抗菌药物
抗生素
药理学
生物
微生物学
作者
Nadia Castaldo,Antonio Vena,Alessandro Limongelli,Daniele Roberto Giacobbe,Matteo Bassetti
出处
期刊:Current Opinion in Infectious Diseases
[Ovid Technologies (Wolters Kluwer)]
日期:2024-01-24
卷期号:37 (2): 80-86
标识
DOI:10.1097/qco.0000000000001003
摘要
Purpose of review To provide a brief overview of drugs in Phase II and III of development for the treatment of acute bacterial skin and skin structure infections (ABSSSI), offering insights into potential customized treatment options. Recent findings Several drugs are currently in advanced stages of evaluation for the treatment of ABSSSI, and numerous molecules are entering in the early development phases. Notably, many of these drugs exhibit unique mechanisms of action and interesting antimicrobial spectrum. Summary Tailoring antibiotic therapy based on patient characteristics, likely pathogens, type, site and severity of ABSSSI is crucial. Given the inherent limitations of available treatments, the development of novel agents is a pivotal avenue. Such advancements hold promise for enhancing treatment efficacy and simplifying drug selection for ABSSSI in everyday clinical practice.
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