ClotTriever System for Mechanical Thrombectomy of Deep Vein Thrombosis

There is increasing evidence that early and comprehensive removal of thrombus in deep vein thrombosis is associated with improved outcomes, including decreased incidence of post-thrombotic syndrome and debilitating long-term symptoms. Catheter-directed thrombolysis is effective for the rapid removal of clot, but it is associated with high bleeding risk. Percutaneous mechanical thrombectomy is a highly effective method for the removal of clot without the use of systemic or catheter-directed thrombolytic therapy. The Inari ClotTriever system (Inari Medical Inc., CA, USA) is a thrombectomy device, which is approved for deep vein thrombosis by the US FDA in 2017. Herein we review the current treatment strategies using the ClotTriever system, its specifications, indications and current state of literature.Deep venous thrombosis is a common disease that causes blood clots in the veins. Complete removal of clot is associated with better outcomes, including decreased incidence of post-thrombotic syndrome (symptoms including leg heaviness, pain, cramping, swelling and discomfort). The ClotTriever system (Inari Medical, Inc., CA, USA) is a device approved for the removal of clot in veins without using clot-busting medications that increase bleeding risk. This review describes the types of devices, indications and current research.