Lipoteichoic Acid and Peptidoglycan fromStaphylococcus aureusSynergistically Induce Neutrophil Influx into the Lungs of Mice

Staphylococcus aureus is an important pathogen in nosocomial pneumonia. Lipoteichoic acid (LTA) and peptidoglycan (PepG) are part of the staphylococcal cell wall. Here we show that LTA and PepG act in synergy to cause polymorphonuclear cell recruitment in the pulmonary compartment during S. aureus pneumonia.