医学
血管生成
癌症
药物输送
癌症研究
药品
癌症治疗
不利影响
药理学
重症监护医学
内科学
纳米技术
材料科学
作者
Yihai Cao,Robert Langer
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2010-01-20
卷期号:2 (15)
被引量:72
标识
DOI:10.1126/scitranslmed.3000399
摘要
Drugs that block angiogenesis are important components of first-line therapies for a number of human cancers. However, some of these agents have undesirable effects on the patient. Optimal delivery systems must be developed to maximize clinical benefits and minimize adverse effects in cancer patients. In this Perspective, we discuss these drug-related issues and propose ways to optimize antiangiogenic therapy by the development of new drug delivery systems.
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