Copper‐Catalyzed Cross‐Coupling of Alkyl and Aryl Grignard Reagents with Alkynyl Halides

Good old copper! A new general procedure to couple aliphatic and aromatic Grignard reagents with alkynyl halides under copper catalysis is described (see scheme; NMP=N-methylpyrrolidinone). The reaction is chemoselective and allows preparation of a vast array of simple and functionalized internal alkynes in high yields.