免疫系统
转移
生物标志物
癌症
功能（生物学）
癌症转移
癌细胞
癌症研究
生物
免疫学
细胞生物学
遗传学
作者
Karine Flem‐Karlsen,Øystein Fodstad,Ming Tan,Caroline E. Nunes‐Xavier
标识
DOI：10.1016/j.trecan.2018.03.010
摘要
B7-H3, a member of the B7 family of immunoregulatory proteins, is overexpressed in cancer and promotes tumor growth, metastasis, and drug resistance. We discuss here the involvement of B7-H3 in cancer that goes beyond its immune regulatory function, and discuss the potential of B7-H3 as a biomarker and therapeutic target.
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