Studies on Dehydroalanine Derivatives. I. Synthesis of N-Carboxy-dehydroalanine Anhydride

Abstract N-Carboxy dehydroalanine anhydride was first synthesized from carbobenzoxy dehydroalanine. The structure of the N-carboxy anhydride was confirmed by the analysis of its infrared spectrum and by the investigation of its chemical behavior. The hydrolytic reaction of the N-carboxy anhydride was compared with that of N-carboxy Dl-alanine anhydride, and it was supposed that dehydroalanine carbamic acid might exist stably in dioxane at ordinary temperature.