comparative study on arterial blood gas analysis among COPD patients and non-COPD patients

Background: Chronic obstructive pulmonary disease (COPD) was confused with so many diseases but as the knowledge and medical skill advance gradually a dramatic change could be observed about all diseases. Cigarette smoking is a leading cause of COPD. Objective: The study principally aims to compare arterial blood gas analysis among patients having chronic obstructive pulmonary disease and healthy control cases. Methodology: A cross sectional study was conducted in 200 patients attended a department with 100 COPD patients and 100 healthy patients. Based on inclusion and exclusion criteria patients were recruited. All patients were under go through ABG analysis. Informed consent was obtained from each patient. P value less than 0.05 considered statistically significant. Results: The results of present study indicated that there were significantly greater alteration in the blood gases and acid base chemistry, particularly PaO2, PaCO2 in patients who show evidence of various complications mentioned earlier. Conclusion: It has thus been inferred that although COPD patients had pH within the normal range the majority of them had low normal values. This study concluded that all parameters of ABG were statistically significantly deranged in chronic bronchitis, emphysema and chronic bronchitis with emphysema patients.