Nondrug-related erythema multiforme-like eruption in a mild case of COVID-19

The diagnostic and prognostic significance of cutaneous affection in COVID-19 remains unclear. Some of the reported skin manifestations including erythema multiforme were considered associated cutaneous adverse drug reactions. Furthermore, it was suggested that erythema multiforme can be associated with good prognosis for COVID-19 infection. This case report, likewise, describes a patient with mild symptoms of COVID-19, presenting with localized erythema multiforme-like lesions of the palms. The skin lesions appeared before receiving any medications. This supports that erythema multiforme can be a cutaneous presentation of COVID-19, rather than a drug eruption.