医学
T790米
肿瘤科
阿波罗
内科学
肺癌
癌症
腺癌
ROS1型
生物
动物
作者
Shun Lu,Q. Wang,G. Zhang,Xing-Duo Dong,Cheng‐Ta Yang,Yong‐Seok Song,G-C. Chang,Ya-Pi Lu,Hui Pan,C-H. Chiu,Z. Wang,Jinlun Feng,Jingjing Zhou,Xiaoheng Xu,Robin Guo,J. Chen,Haihua Yang,Y. Chen,Zhuang Yu,H-S. Shiah
标识
DOI:10.1016/j.annonc.2021.08.1813
摘要
Aumolertinib is a novel, irreversible third generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI). APOLLO, a pivotal phase II single-arm study (NCT02981108), has demonstrated progression-free survival (PFS) benefit with a favorable safety profile in pretreated EGFR T790M positive NSCLC patients.
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