A dual-function host–guest antioxidant system for synergistic treatment of diquat poisoning

evaluations demonstrated the excellent detoxification efficacy of this formulation. The EGT/P6AS complex effectively ameliorated DQ-induced organ damage and promoted the normalization of key hematological and biochemical parameters. Notably, treatment with EGT/P6AS resulted in a 50-percentage-point increase in survival rate, underscoring its remarkable therapeutic potential. These favorable outcomes are attributed to a combinatorial mechanism: DQ triggers the release of EGT to counteract peroxidation damage, while free DQ is simultaneously sequestered within the cavity of P6AS.