Study on the prevalence rate and optimal waist circumference cut-off points of obesity for the components of metabolic syndrome in Uygur from Xinjiang

Objective To investigate the prevalence of metabolic syndrome and appropriate cut-off point of waist circumference of abdominal obesity for components of metabolic syndrome in Uygur population in Xinjiang. Methods A questionnaire-based survey, physical examination, and blood testing were conducted according to cluster random sampling in Uygur residents above 18 years old in Xinjiang. There were 3 542 samples collected, based on the International Diabetes Federation (IDF) standard of metabolic syndrome, the relativities of clustering of metabolic syndrome components and different strata of waist circumference for Uygur were analyzed, and looking for the appropriate cut-off points for identifying two or more components of metabolic syndrome within the shortest distance of receiver operating characteristic (ROC) curve. Results According to IDF standard, the waist circumference (85 cm for men, 82 cm for women) corresponded to the shortest distance in ROC curve, at these cut-offs of abdominal obesity for component of metabolic syndrome, the prevalences of metabolic syndrome were 21.3%, 19.5% in men, while 23.0% in women, the prevalence of women was higher than that of men (P<0.05). The prevalences of ≥1, ≥2 components of metabolic syndrome were shown an increasing trend with the increasing size of waist circumference, and the odds ratio of clustering of metabolic syndrome components were also increased significantly. Conclusion The prevalence of metabolic syndrome among Xinjiang Uygur population was higher than that of national level. The cut-off points of waist circumference (85 cm for men, 82 cm for women) combining other components definition of IDF standard were recommended for identifying metabolic syndrome of Uygurs. (Chin J Endocrinol Metab, 2018, 34: 211-216) Key words: Metabolic syndrome; Uygur; Component of obesity; Cut-off points of waist circumference; Prevalence rate