Intravenous injection of diazepam to cubital vein can be complicated by accidental intra-arterial penetration and gangrene.

We present an elbow disarticulation due to accidental intra-arterial injection of diazepam. Considering the risk of inadvertent and accidental intra-arterial injection of diazepam and its subsequent severe sequelae that are reported in the literature, we emphasize that intravenous diazepam should be administered with more hesitancy and care.