Biological Activities Studies and Phase Transfer Catalysts Promoting the One-Pot Synthesis of N-Aryl-N′-(4-Ethyloxy Benzoyl)-Thiourea Derivatives

Abstract A series of N-aryl-N′-(4-ethyloxybenzoyl)-thiourea 3a–h was synthesized under phase transfer catalysis and r.t. conditions. The chemical structure of all compounds were established by IR, 1H NMR, and 13C NMR studies, and all of the compounds were investigated for plant-growth regulating activity. Excitingly, they remarkably enhance root elongation. Keywords: Biological activitiesN-aryl-N′-(4-ethyloxybenzoyl)-thioureaone-pot synthesisphase transfer catalysis Acknowledgments Financial support of this work by the Natural Science Foundation of China (No. 20371040) and the Foundation of Lanzhou Jiaotong University are acknowledged. Notes a The m.p. of 7 is 162–163°C (Lit.17 163–164°C). b The m.p. of 8 is 146–148°C (Lit.12 148°C). a The solution was prepared in the proportion of H2O:DMF = 99.5:0.5, and 0.1 g Tween-80 was added to promote the compound to be dissolved.