A Study of the Preparation Technology of Weichangkang Capsules

Objective: To provide scientific basis for the preparation technology of weichangkang capsules. Methods: The preparation technology of weichangkang capsules and its influencing factors (A. number of decoctions; B. time of decoction; C. amount of water added) were studied with an orthogonal test. The content of astragalnside Ⅳ was determined with TLC as an index for optimizing the extraction technology. Results: All of the 3 factors A, B and C were shown to exert remarkable effects on the extraction of astragaloside Ⅳ from weichangkang capsules. Conclusion: The optimal extraction conditions for the preparation technology of weichangkang capsules were: 3 times of decoction for 2.0, 1.5 and 1.5 h, respectively; addition of 10 volumes of water for the first decoction, 6 volumes water for the second and third decoctions.