For finding a efficiency approach to enhance the reduction ability of hydrongen, the reduction of CuO by as-nonequilibrium plasma hydrogen produced by a DC pulsed glow discharge was studied, and the comparisons with the reduction of CuO by as-molecular hydrogen was done. Under the condition of a pressure of 450 Pa and a temperature of 200 ℃, the reduction time is from 10 min to 60 min, the experimental results show that CuO was reduced with plasma hydrogen to metal copper, while it was unreducible by as-molecular hydrogen. All these results indicated that the reduction ability of hydrogen is enhanced by transforming as-molecular H_2 to as-plasma hydrogen.