Recent advances in nickel catalyzed Suzuki-Miyaura cross coupling reaction via C-O& C-N bond activation

Research on transition metal catalysis is advancing day by day. Unlike the conventional precious metal based catalysis, the researchers are now focussing on exploring the applicability of earth-abundant first row transition elements as catalysts for C-C coupling reactions. Among them, the Suzuki-Miyaura coupling reaction greatly impacts the industrial catalytic processes. Nickel catalyzed Suzuki-Miyaura coupling is a great topic of interest for organic chemists over the last few decades. But, the mitigation of halogen waste is the major environmental concern associated with the traditional Suzuki coupling reaction. In this concern, various abundant and cheap electrophiles such as carboxylic acid derivatives, phenol derivatives, and amides have a remarkable priority in replacing the organic halides. In this strategy, the core C-O and C-N bonds were activated to form the C-C coupling products. Based on the advantages of Ni-catalysis, the research is directed towards exploring the various Ni-based catalytic systems for the successful Suzuki coupling reaction by activating C-O and C-N bonds. The recent reports are highly motivated toward green metrics. In the current review, we would like to summarize the recent advances in the Ni-catalyzed Suzuki coupling via C-O and C-N bond activation.