尘肺病
病态的
动物模型
疾病
医学
病理
内科学
作者
Runsu Hou,Yuehua Tian,J S Li
出处
期刊:PubMed
[National Institutes of Health]
日期:2022-07-20
卷期号:40 (7): 547-552
标识
DOI:10.3760/cma.j.cn121094-20210425-00230
摘要
Pneumoconiosis is an occupational lung disease with the highest incidence in China. There is no effective treatment drug at present. Animal and cell models are the basis for exploring its pathogenesis and developing effective drugs. In this paper, we sort out the methods of animal models of pneumoconiosis and the different cell models induced by dust in recent years, by analyzing and summarizing the advantages and disadvantages, modeling time, pathology and changes in important indicators of different preparation methods of animal models, as well as different cell models induced by the dust to simulate different pathological models and pathological stages, to provide basis for the application and improvement of pneumoconiosis model.
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