医学
特应性皮炎
食物过敏
皮肤屏障
过敏
皮肤病科
敏化
免疫学
作者
Elizabeth Huiwen Tham,Kiwako Yamamoto‐Hanada,Agnes Sze Yin Leung,Yukihiro Ohya
摘要
Food allergy is postulated to originate from cutaneous sensitization through a disrupted skin barrier, particularly in atopic dermatitis (AD). Strategies for food allergy prevention currently centre around early allergic food introduction, but there is now increasing evidence for the role of early skin barrier restoration in the form of prophylactic emollient therapy and early aggressive, proactive treatment of established AD for food allergy prevention. Research gaps that remain to be addressed include the type of emollient or anti-inflammatory medication, which confers the greatest efficacy in preventive or proactive skin treatment, respectively, the duration of therapy, and the window of opportunity for these interventions.
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