免疫化学
再生(生物学)
精子发生
三价铁
肝再生
内科学
男科
内分泌学
生物
污渍
染色
化学
医学
细胞生物学
免疫学
抗体
遗传学
铁质
有机化学
作者
Xuan Chen,Deying Zhang,Xing Liu,Guanghui Wei
出处
期刊:PubMed
日期:2007-08-01
卷期号:13 (8): 700-5
摘要
To investigate the expression of the augmenter of liver regeneration (ALR) in cryptorchidism spermatogenic cells.Twenty cryptorchidism rat models were established by surgery, 10 included as normal controls and anther 10 as sham-surgery controls. The expression of ALR was detected by immunochemistry, the COX II level measured by immunofluorescence and the ferric iron contents assayed by Perls stain.ALR expressed intensively in the spermatogonia of the control groups but in a signigicantly diminished manner in the cryptorchidism group. No significant difference was found in the COX II level between any two groups of the same age. Ferric iron content of the PND30 cryptorchids decreased significantly (P < 0.05).ALR may play an important role in early spermatogenesis. Metabolism dysfunctions caused by ALR defection might be a crucial mechanism for aspermatogenesis of cryptorchidism.
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